Our lab studies genetic and environmental risks for autism. In addition, we study molecular and brain mechanisms that underlie pain sensation. Research includes use of CRISPR/Cas, AAV gene therapy vectors, single cell RNA-seq, molecular biology and behavior. Our long-term goal is to uncover new treatments for chronic pain and neurodevelopmental disorders, like autism and Angelman syndrome.
Research in our lab has been made possible by generous support from the following:
NIH/National Institute of Environmental Health Sciences (NIEHS)
NIH/National Institute of Mental Health (NIMH)
NIH/National Institute of Neurological Disorders and Stroke (NINDS)
Rett Syndrome Research Trust
Angelman Syndrome Foundation
Foundation for Angelman Syndrome Therapeutics
Autism Speaks
Simons Foundation
Searles Scholars Program
NC Translational and Clinical Sciences Institute (NC TraCS)
Rita Allen Foundation
Whitehall Foundation
The Ester A. & Joseph Klingenstein Fund
The Alfred P. Sloan Foundation
Brain & Behavior Research Foundation